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Anaemia developed in 73% of patients (38% <100 g/L, 8% <80 g/L), though definite new haemolysis was present in only 11%. Ninety-five percent of patients developed marked acanthocytosis, echinocytosis and/or spheroacanthocytosis, not observable with prior treatment with other ALK-inhibitors. Her book, The Big 50: TheВ Detroit Red Wings is available from Amazon, Barnes & Noble and Triumph Books.В Personalized copies available via her e-mail.We reviewed haematological investigations for 43 patients treated at a single centre with alectinib, an inhibitor of anaplastic lymphoma kinase (ALK) which is considered standard first-line treatment for patients with ALK-rearranged advanced non-small cell lung cancer. James at Follow her on Twitter Read more on the Detroit Red Wings and sign up for our Red Wings newsletter. More: Moritz Seider, Lucas Raymond want to show Detroit Red Wings 'are taking big steps'Д¬ontact Helene St. Seider quarterbacked one power play unit, and Raymond was part of the other. Seider had a hand in BertuzziвЂ™s first and fourth goals, and Raymond in the third. Both rookies had debuts to remember: Huge cheers when they were introduced in pre-game ceremonies, and an assist. ItвЂ™s only been a little more than two years since Yzerman drafted defenseman Moritz Seider and a year since forward Lucas Raymond joined the organization. The NHLВ will review the incident to determine if further disciplinary action is warranted, but it's doubtful Larkin will be suspended. Joseph and Jan Rutta, who jumped Larkin, were each assessed roughing penalties. Larkin retaliated, taking a swipe at JosephвЂ™s head and officials assessed Larkin a match penalty, ejecting him from the game. Mathieu Joseph hit himВ in the neck/shoulder area LarkinвЂ™s season was cut short last April when he suffered a neck injury that required hospitalization. The second period took a rough turn for Larkin.

Larkin earned the first goal of the season when he skated to the net as Robby Fabbri took a shot from the left flank. Larkin was named at the start of last season, but the pandemic prevented any recognition before fans. Steve Yzerman, Nicklas Lidstrom and Henrik Zetterberg, along with Alex Delvecchio, Red Berenson, Paul Woods, Nick Libbett, Dennis Hextall and Mickey Redmond were on the ice to recognize Larkin as the franchiseвЂ™s 37th captain. Larkin finally got to celebrate his captaincy before fans, introduced before the game as a whoвЂ™s who of former captains lined a red carpet. MORE: Wings' Tyler Bertuzzi calls refusing COVID-19 vaccine 'a life choice' Captain celebrates, leaves RELATED: Steve Yzerman, Nicklas Lidstrom welcomeВ Larkin toВ Wings captain's row Bertuzzi completed the hat trick at 12:29 when he took a pass from Robby Fabbri and ripped the puck into TampaвЂ™s net. In the opening minute of the second period, Bertuzzi took a pass from Leddy, weaved from two defenders and sniped the puck past Vasilevskiy.Д«ertuzzi upped the score to 3-0 when he pounced on Adam ErneвЂ™s rebound in the paint. It didnвЂ™t take long for Bertuzzi to drive home just how much the Wings missed him last season, when a back injury cost him all but the first nine games. It took five seconds for Nikita Kucherov to convert. Robby Fabbri went to the penalty box with 4:11 to play, putting the Lightning on power play for the seventh time, and Tampa added to the skater advantage by pulling Andrei Vasilevskiy. Newcomer Nick Leddy earned his second assist on NamestnikovвЂ™s goal. Ondrej Palat interrupted BertuzziвЂ™s hat trick and Steven Stamkos converted twice on power plays less than two minutes apart to reduce the WingsвЂ™ lead to 4-3 by the end of the second period.Д«ertuzziвЂ™s fourth goal and NamestnikovвЂ™s first restored a cushion early in the third period. Larkin was gone by then, ejected for retaliating against a hit. The blown lead dampens a memorable night for Tyler Bertuzzi:В He scored a hat trick in the second period and added a fourth goal in the third period. The Lightning owned the puck in overtime, and Ondrej Palat secured a 7-6 victory with his second goal of the game. The Wings fed on the energy, but their lack of discipline dissolved their leadВ to a tie in regulation.

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It was the first time since the pandemic shuttered the NHL in March 2020 that a full house had been possible. Watch Video: Tyler Bertuzzi: Detroit Red Wings showed something in opening night OT lossДЄ lively crowd and a captainвЂ™s row of former greats heralded the Detroit Red WingsвЂ™ opening night.ДЄll started well as Dylan Larkin scored, delighting fans that crowded into Little Caesars Arena on a rainy Thursday night to see the Wings take on the defending Stanley Cup champion Tampa Bay Lightning.

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